精密磨床转台静压轴承的强健化设计

针对精密磨床转台静压轴承性能仿真数据与其回转精度实测数据不一致的问题，为提高转台静压轴承的设计水平，提出了静压轴承的强健化设计方法。该方法考虑了轴承结构参数在轴承全生命周期内的变化，分析了半径间隙、油腔尺寸、节流比及润滑油黏度在设计、加工、装配和服役4个阶段的变化规律，重点研究了半径间隙在各阶段对轴承性能造成的影响，给出了转台静压轴承的强健化设计流程。通过一个径向轴承的设计实例对该强健化设计方法进行了说明，并将设计结果与传统设计进行了对比。对比的指标是轴承在4个阶段的刚度、承载力和温升，这3个指标对轴承回转精度有直接影响。研究表明：进行强健化设计后，在生命周期内静压轴承的刚度和承载力的变化量为10%~27%，温度的变化量为0.5%~1.6%，较传统设计更能保证转台回转精度的稳定。     

和尚桥选矿厂中碎大块干选抛尾改造实践

针对马钢和尚桥选矿厂入选矿石品位低、选矿比大、选矿成本高、尾矿浓密机长期超负荷运行的问题，进行了中碎产品大块干式预选抛尾工艺研究与生产工艺改造。结果表明：①选用CTDG1220型磁滑轮对现场中碎产品进行干式预选抛尾，可抛出产率12.38%、全铁品位10.31%、磁性铁品位0.80%的废石；干抛精矿全铁品位20.00%、磁性铁品位7.29%、全铁回收率达93.21%、磁性铁回收率达98.42%，后续作业矿石铁品位提高了1.20个百分点。②细碎及其后续系统的负荷显著下降，有利于后续系统的稳定运行；每年产出的74.28万t废石可作为砂石骨料销售。③新增系统年创造经济效益3 728.28万元。     

Knocking down USP39 Inhibits the Growth and Metastasis of Non-Small-Cell Lung Cancer Cells through Activating the p53 Pathway

Ubiquitin-specific protease 39 (USP39), a member of the deubiquitinating enzyme family, has been reported to participate in cytokinesis and metastasis. Previous studies determined that USP39 functions as an oncogenic factor in various types of cancer. Here, we reported that USP39 is frequently overexpressed in human lung cancer tissues and non-small-cell lung cancer (NSCLC) cell lines. USP39 knockdown inhibited the proliferation and colony formation of A549 and HCC827 cells and decreased tumorigenic potential in nude mice. Specifically, knocking down USP39 resulted in cell cycle arrest at G2/M and subsequent apoptosis through the activation of the p53 pathway, including upregulation of p21, cleaved-cas3, cleaved-cas9 and downregulation of CDC2 and CycinB1. Moreover, USP39 knockdown significantly inhibited migration and invasion of A549 and HCC827 cells, also via activation of the p53 pathway, and downregulation of MMP2 and MMP9. Importantly, we verified these results in metastasis models in vivo. Collectively, these results not only establish that USP39 functions as an oncogene in lung cancer, but reveal that USP39 has an essential role in regulating cell proliferation and metastasis via activation of the p53 pathway.     

基于多变量时间序列及向量自回归机器学习模型的水驱油藏产量预测方法

提出了一种基于多变量时间序列(MTS)及向量自回归(VAR)机器学习模型的水驱油藏产量预测方法,并进行了实例应用。该方法在井网分析的基础上通过MTS分析对注采井组数据进行优选,并将井组内不同采出井产油量及注入井注水量作为彼此相关的时间序列,通过建立VAR模型从多个时间序列中提取出相互作用规律,挖掘注采井间流量的依赖关系从而进行产量预测。水驱油藏历史生产数据分析结果表明,与数值模拟历史拟合结果相比,机器学习模型产量预测结果具有更高精度,同时不确定性分析提升了预测结果的安全性。通过脉冲响应分析对注入井的采油贡献量进行评价,可为注水开发方案调整提供理论指导。     

Synergistic effect of bulk phase doping and layered-spinel structure formation on improving electrochemical performance of Li-Rich cathode material

In this study, La was doped into the lithium layer of Li-rich cathode material and formed a layered-spinel hetero-structure. The morphology, crystal structure, element valence and kinetics of lithium ion migration were studied by field emission scanning electron microscope (FESEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and electrochemical impedance spectroscopy (EIS). The La doped lithium-rich cathode material exhibited similar initial discharge capacity of 262.8 mAh g^?1 at 0.1 C compared with the undoped material, but the discharge capacity retention rate can be obviously improved to 90% after 50 cycles at 1.0 C. Besides that, much better rate capability and Li⁺ diffusion coefficient were observed. The results revealed that La doping not only stabilized the material structure and reduced the Li/Ni mixing degree, but also induced the generation of spinel phase to provide three-dimensional diffusion channels for lithium ion migration. Moreover, the porous structure of the doped samples also contributed to the remarkable excellent electrochemical performance. All of these factors combined to significantly improve the electrochemical performance of the material.     

Facile Fabrication of Luminescent Eu(III) Functionalized HOF Hydrogel Film with Multifunctionailities: Quinolones Fluorescent Sensor and Anticounterfeiting Platform

The luminescent hydrogen-bonded organic framework (HOF) based films have become one of the most remarkable materials for optical application, thus, developing facile synthesis methods and establishing multifunctional applications for HOF-based luminescent materials are essential. Herein, a dual-emitting Eu³⁺-functionalized HOF hydrogel film ( 1 ) is fabricated successfully. 1 emits a blue-green long afterglow when turning off the UV lamp, and the long afterglow lifetime gets to 1.99 s. 1 performs great selectivity, high sensitivity, and low detection limit toward ofloxacin and flumequine, and the sensing toward ofloxacin and flumequine is in accord with the chroma and ratio modes. The fluorescent response mechanisms of 1  toward ofloxacin and flumequine are investigated in depth, which are further utilized to build an anticounterfeiting platform with high-level security. The film-based anticounterfeiting platform can conduct information encryption on demand inline with different fluorescent responses and can also fetch specific information by controlling the long afterglow intensity and excited light. This study not only provides a representative case of the fabrication of dual-emitting Eu³⁺-functionalized HOF-based hydrogel film but also opens the possibility of HOF-based film as intelligent luminescent materials with multifunctionalities.     

临兴区块新型储层保护钻井液技术研究与应用

临兴区块地层非均质性强,具有低孔、低渗、低温、低压的特点,需要后期压裂改造,才能实现工业化气流.随着该区域的钻井数量逐渐增多,储层伤害问题日益突出,笔者对地层进行了敏感性分析,在此基础上,研制了超双疏剂,并对其性能进行了评价.结果表明:超双疏剂能够使岩心孔喉表面润湿性由亲水亲油向疏水疏油转变,有效降低低渗储层发生自吸水锁概率,达到保护储层的目的;同时,3％质量分数的超双疏剂比传统的抑制剂KCl和聚醚胺等具有更好的抑制性能.现场应用表明,加入超双疏剂后的钻井液黏度低、切力高、老化前后性能稳定,应用双疏钻井液体系后现场平均机械钻速提高32.33％,井眼扩大率降低33.89％,作业井日产量平均在35973.5 m3/d.     

Review of hydrogen crossover through the polymer electrolyte membrane

Proton exchange membrane fuel cell (PEMFC) is considered to be a promising, clean, and efficient energy conversion device. At present, the main challenges faced by the application of PEMFC in the automotive are cost and durability. Hydrogen from anode to the cathode through polymer electrolyte membrane (i.e. crossover hydrogen) affects the durability of fuel cells. In this paper, the existing literature on hydrogen crossover is reviewed and summarized from consequences, causes, mitigation measures, and detection methods. The influences of hydrogen crossover on the components and performance are discussed. The causes are analyzed from structural permeation and membrane degradation. The methods of alleviating the degradation of the membrane are summarized. The electrochemical and non-electrochemical monitoring methods are described, and the segmented current method is explained separately. The existing problems and research prospects are put forward, which lays a foundation for further research on hydrogen crossover and improvement fuel cell durability.